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PTGX

PTGX

Healthcare · Biotechnology

$109.27-2.84%
Mkt Cap: $7.03B

Performance

PTGX (PTGX) Stock Analysis 2026

Rule-based · Updated daily · Not financial advice

PTGX (PTGX) operates in the Biotechnology space within the Healthcare sector. With a market cap of $7.0B, it qualifies as a small-cap company. Revenue is expanding quickly, but the company has yet to translate that growth into consistent profits — a common risk in high-growth early-stage businesses.

Bull Case2
  • Revenue grew 99% year-over-year — exceptional top-line expansion
  • Current ratio of 17.8× — ample short-term liquidity
Bear Case5
  • Negative profit margin of -154.9% — company is currently unprofitable
  • Negative ROE of -17.1% — shareholder equity is being eroded
  • No dividend history — total return depends entirely on price appreciation
  • Price is near its 52-week high — limited near-term upside, higher pullback risk
  • High beta of 1.83 — this stock is significantly more volatile than the broader market

Verdict

Avoid

Significant fundamental concerns outweigh positives. High risk at current levels.

AI Insight

Powered by Claude

AI-generated analysis for informational purposes only. Not financial advice.

Related Articles

Revenue & Results

Dividends

This stock does not pay dividends.

If You Had Invested…

Hypothetical return based on historical prices

$

* Dividend reinvestment calculated at ex-date price. For informational purposes only.

Earnings

EPS (TTM)

$-1.81

P/E (TTM)

Fwd P/E

-159.6

Earnings History

SEC EDGAR · official filings

SEC filings

SEC Filings

Official EDGAR documents

All filings

Key Statistics

Valuation

Market Cap$7.03B
P/E Ratio
Forward P/E-159.60
P/B Ratio
PEG Ratio
EPS (TTM)$-1.81

Trading

Open
Day High
Day Low
52W High$113.66
52W Low$49.38
Volume
Avg Volume (3M)717,968
Beta1.83

Dividends

Dividend Yield
Annual Rate
Ex-Div Date
Payout Ratio0.00%

Profitability

Profit Margin-154.88%
Operating Margin-6.47%
ROE-17.06%
ROA-12.37%
Revenue Growth99.00%
Earnings Growth

Balance Sheet

Total Revenue$74.06M
Total Debt$9.78M
Debt / Equity1.49
Current Ratio17.76
Free Cash Flow$-77,664,624

Fair Value Estimates

Current price: $109.27

Graham Number

√(22.5 × EPS × Book Value)

N/A

Benjamin Graham's intrinsic value formula. Assumes a fair stock trades at no more than 22.5× the product of EPS and book value per share.

Bazin Ceiling Price

Avg. Annual DPS (5Y) ÷ 6%

N/A

Décio Bazin's dividend-based ceiling. The max price you should pay so that dividends alone deliver at least 6% annual yield on your cost basis.

These are simplified estimates. Not financial advice.

Buy & Hold Checklist

Quality criteria for long-term holding

4/10

57% score

Pays dividends

No dividend history found

Dividend consistency (5Y+)

Uninterrupted dividend payments for at least 5 years

ROE above 10%

-17.1%

Return on equity — measures how efficiently capital is used

Positive profit margin

-154.9%

Net profit margin must be positive — company earns more than it spends

Revenue growth (annual)

+99.0%

Annual revenue must be growing compared to the prior year

Earnings growth (annual)

Annual earnings must be growing compared to the prior year

Debt/Equity below 2×

1.49×

Low financial leverage reduces risk of distress

Current ratio above 1

17.76×

Short-term assets must cover short-term liabilities

Daily liquidity above $5M

$78M/day

High trading volume ensures easy entry and exit

Dividend yield above 0%

Stock must distribute income to shareholders

Related Assets

Healthcare

About PTGX

Protagonist Therapeutics, Inc. operates as a discovery and development company in the United States. It develops Icotyde, a first-in-class investigational targeted oral peptide for the treatment of adults and pediatric patients 12 years of age and older with moderate-to-severe plaque psoriasis; and Rusfertide, a first-in-class investigational injectable mimetic of the natural hormone hepcidin in Phase 3 development for the treatment of the rare blood disorder polycythemia vera. The company is also developing PN-881, a potential best-in-class oral peptide IL-17 antagonist, for the treatment of immune-mediated skin diseases in Phase 1 clinical trials; PN-477 and PN-458, which are development candidates for the treatment of obesity; PN-8047, an orally administered hepcidin functional mimetic small molecule; L-4R alpha antagonist for the treatment of atopic dermatitis and moderate-to-severe asthma; and amylinR-based oral and subcutaneous mono- and poly-agonists for the treatment of obesity. Protagonist Therapeutics, Inc. was incorporated in 2006 and is headquartered in Newark, California.

Sector

Healthcare

Industry

Biotechnology

Location

Newark, United States

Employees

131