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ALNY

ALNY

Healthcare · Biotechnology

$280.45-2.55%
Mkt Cap: $37.44B

Performance

ALNY (ALNY) Stock Analysis 2026

Rule-based · Updated daily · Not financial advice

ALNY (ALNY) operates in the Biotechnology space within the Healthcare sector. With a market cap of $37.4B, it qualifies as a mid-cap company. The company is growing revenue strongly while maintaining healthy profitability — a combination that investors typically reward with a premium valuation.

Bull Case7
  • Forward P/E (20.4×) is lower than trailing P/E (70.6×) — analysts expect earnings to improve
  • Revenue grew 96% year-over-year — exceptional top-line expansion
  • Healthy profit margin of 12.6%
  • ROE of 90.4% shows management efficiently converts equity into profit
  • Current ratio of 3.1× — ample short-term liquidity
  • Price is near its 52-week low — potential entry point with asymmetric upside
  • Low beta of 0.27 — less volatile than the market, suitable for conservative portfolios
Bear Case3
  • High P/E of 70.6× implies high expectations already priced in — leaves little room for disappointment
  • High debt-to-equity of 276.20× increases financial risk, especially with elevated interest rates
  • No dividend history — total return depends entirely on price appreciation

Verdict

Strong Buy

Multiple fundamental strengths with few red flags. Long-term buyers may find this compelling.

AI Insight

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AI-generated analysis for informational purposes only. Not financial advice.

Related Articles

Revenue & Results

Dividends

This stock does not pay dividends.

If You Had Invested…

Hypothetical return based on historical prices

$

* Dividend reinvestment calculated at ex-date price. For informational purposes only.

Earnings

Next Earnings

Jul 30, 2026

44

days

EPS (TTM)

$3.97

P/E (TTM)

70.6

Fwd P/E

20.4

Earnings History

SEC EDGAR · official filings

SEC filings

SEC Filings

Official EDGAR documents

All filings

Key Statistics

Valuation

Market Cap$37.44B
P/E Ratio70.64
Forward P/E20.37
P/B Ratio
PEG Ratio0.48
EPS (TTM)$3.97

Trading

Open
Day High
Day Low
52W High$495.55
52W Low$276.94
Volume
Avg Volume (3M)1,114,253
Beta0.27

Dividends

Dividend Yield
Annual Rate
Ex-Div Date
Payout Ratio0.00%

Profitability

Profit Margin12.55%
Operating Margin23.02%
ROE90.36%
ROA10.06%
Revenue Growth96.40%
Earnings Growth

Balance Sheet

Total Revenue$4.29B
Total Debt$2.97B
Debt / Equity276.20
Current Ratio3.13
Free Cash Flow$204.71M

Fair Value Estimates

Current price: $280.45

Graham Number

√(22.5 × EPS × Book Value)

$26.83

-90.4% downside

Benjamin Graham's intrinsic value formula. Assumes a fair stock trades at no more than 22.5× the product of EPS and book value per share.

Bazin Ceiling Price

Avg. Annual DPS (5Y) ÷ 6%

N/A

Décio Bazin's dividend-based ceiling. The max price you should pay so that dividends alone deliver at least 6% annual yield on your cost basis.

These are simplified estimates. Not financial advice.

Buy & Hold Checklist

Quality criteria for long-term holding

5/10

71% score

Pays dividends

No dividend history found

Dividend consistency (5Y+)

Uninterrupted dividend payments for at least 5 years

ROE above 10%

90.4%

Return on equity — measures how efficiently capital is used

Positive profit margin

12.6%

Net profit margin must be positive — company earns more than it spends

Revenue growth (annual)

+96.4%

Annual revenue must be growing compared to the prior year

Earnings growth (annual)

Annual earnings must be growing compared to the prior year

Debt/Equity below 2×

276.20×

Low financial leverage reduces risk of distress

Current ratio above 1

3.13×

Short-term assets must cover short-term liabilities

Daily liquidity above $5M

$312M/day

High trading volume ensures easy entry and exit

Dividend yield above 0%

Stock must distribute income to shareholders

Related Assets

Healthcare

About ALNY

Alnylam Pharmaceuticals, Inc. discovers, develops, manufactures, and commercializes therapeutics based on ribonucleic acid interference in the United States, Europe, and internationally. The company offers ONPATTRO for hereditary transthyretin-mediated (hATTR) amyloidosis; AMVUTTRA for ATTR and hATTR amyloidosis; Leqvio for hypercholesterolemia; Qfitlia for hemophilia A or B; GIVLAARI for acute hepatic porphyria; and OXLUMO for primary hyperoxaluria type 1. It also develops a range of products in Phase 3 trial, such as Nucresiran for ATTR amyloidosis; Zilebesiran for hypertension; Cemdisiran for myasthenia gravis, paroxysmal nocturnal hemoglobinuria, and geographic atrophy; and Elebsiran for hepatitis D virus infections. In addition, the company is developing various products in Phase 2 trial, including Rapirosiran for metabolic dysfunction-associated steatohepatitis; ALN-ANG3 for diabetic kidney disease; ALN-4324 for type 2 diabetes mellitus; Mivelsiran for cerebral amyloid angiopathy, as well as in Phase 1 trial for Alzheimer's disease; and ALN-6400 for bleeding disorders. Further, it develops a range of products in Phase 1 trial, such as ALN-2232 for obesity and weight management; ALN-PNP for non-alcoholic fatty liver disease; ALN-APOC3 for dyslipidemia; ALN-CIDEB for metabolic dysfunction-associated steatohepatitis; ALN-HTT02 for Huntington's disease; ALN-5288 for Alzheimer's disease; ALN-SOD for SOD1 amyotrophic lateral sclerosis; ALN-SNCA for Parkinson's disease; AG-236 for polycythemia vera; ALN-CFB for paroxysmal nocturnal hemoglobinuria; ALN-BCAT for hepatocellular carcinoma; and ALN-4285, ALN-4915, and ALN-F1202 for healthy volunteers. The company has collaborations with Regeneron Pharmaceuticals, Inc.; Roche Holding AG; Sanofi S.A.; Novartis AG; PeptiDream, Inc; Dicerna Pharmaceuticals, Inc.; and Ionis Pharmaceuticals, Inc. Alnylam Pharmaceuticals, Inc. was founded in 2002 and is headquartered in Cambridge, Massachusetts.

Sector

Healthcare

Industry

Biotechnology

Location

Cambridge, United States

Employees

2,500